top of page

New publication by Wolfgang Knoll, Christoph Kleber, and Roger Hasler

Verena Hauer

New publication by Wolfgang Knoll, Christoph Kleber, and Roger Hasler together with colleagues from the University of Ulm, titled “Specific gFET-Based Aptasensors for Monitoring of Microbiome Quality: Quantification of the Enteric Health-Relevant Bacterium Roseburia Intestinalis”.

 

This research highlights the development of a graphene-based biosensor (gFET) functionalized with aptamers to detect Roseburia intestinalis, a gut bacterium linked to obesity and inflammation, with high sensitivity and specificity. The identified and synthesized individual aptamers, employed as bioreceptors on the sensor surface, show a high affinity and are suitable for large-scale production with the potential for commercial applications. The sensor effectively distinguishes R. intestinalis from other gut bacteria in real samples, demonstrating sufficient sensitivity for quantitative supportive monitoring of probiotic supplementation strategies in biomedicine.






10 views0 comments

Comments


bottom of page