New Publication
A new publication in Biosensors and Bioelectronics X explores the potential of electrolyte-gated organic transistors (EGOTs) enabling DNA detection. The study is the result of an international research collaboration with the department of Life Sciences from the Università di Modena e Reggio Emilia, and includes Katharina Schmidt, Roger Hasler, Jakub Dostálek and Wolfgang Knoll from Danube Private University (DPU) among its co-authors.
The study explores the use of the high-mobility donor-acceptor polymer DPP-DTT in electrolyte-gated organic transistors (EGOTs) for label-free biosensing. By functionalizing the gate electrode with DNA probes, the platform enabled the specific detection of mitochondrial DNA (mtDNA), a biomarker associated with multiple sclerosis, over a concentration range from 70 pM to 5 nM. The work demonstrates the excellent stability and sensing performance of DPP-DTT-based EGOTs, highlighting their potential as sensitive, low-voltage biosensing platforms for future biomedical research and diagnostic applications.
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